Evaluation of serum cysteine-rich protein 61 levels in patients with coronary artery disease-Reference-Cited by-同舟云学术

Evaluation of serum cysteine-rich protein 61 levels in patients with coronary artery disease

Published:2018-04 Issue:4 Volume:12 Page:329-339
ISSN:1752-0363
Container-title:Biomarkers in Medicine
language:en
Short-container-title:Biomarkers in Medicine

Author:

Deng Jingang¹,Qian Xiaoxian²,Li Jianping¹,Li Yanghua¹,Li Yang¹,Luo Yijun¹

Affiliation:

1. Division of Cardiology, Shenzhen Tenth People's Hospital, Shenzhen, Guangdong, China

2. Division of Cardiology, The Third Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China

Abstract

Aim: The aim is to evaluate serum cysteine-rich protein 61 (Cyr61) levels in patients with coronary artery disease (CAD). Patients & methods: Serum Cyr61 levels were measured in 180 patients with CAD and 74 participants without CAD. Results: Serum Cyr61 levels were significantly higher in CAD patients. Patients with acute coronary syndrome showed significantly higher Cyr61 than those with stable angina pectoris. Serum Cyr61 levels in complex lesion group were significantly higher. Serum Cyr61 was positively correlated with Gensini score and C-reactive protein. Multivariable logistic regression analyses demonstrated that serum Cyr61 levels were independently correlated with the existence of CAD (p = 0.01). Conclusion: Our study suggested Cyr61 as a potential biomarker in characterizing CAD and therapeutic target for CAD.

Publisher

Future Medicine Ltd

Subject

Biochemistry, medical,Clinical Biochemistry,Drug Discovery

Link

https://www.futuremedicine.com/doi/pdf/10.2217/bmm-2017-0390

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