1. Division of Cardiology, C.A.S.T., Azienda Ospedaliero-Universitaria “Policlinico-Vittorio Emanuele”, University of Catania, Catania 95123, Italy
2. Division of Cardiology, “Pierangeli” Clinic, Pescara 65124, Italy
3. The Zena & Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA