GARFIELD-AF: a worldwide prospective registry of patients with atrial fibrillation at risk of stroke-Reference-Cited by-同舟云学术

GARFIELD-AF: a worldwide prospective registry of patients with atrial fibrillation at risk of stroke

Published:2021-01 Issue:1 Volume:17 Page:19-38
ISSN:1479-6678
Container-title:Future Cardiology
language:en
Short-container-title:Future Cardiology

Author:

Bassand Jean-Pierre¹²^ORCID,Apenteng Patricia N³,Atar Dan⁴⁵,Camm A John⁶,Cools Frank⁷,Corbalan Ramon⁸,Fitzmaurice David A³,Fox Keith AA⁹,Goto Shinya¹⁰,Haas Sylvia¹¹,Hacke Werner¹²,Jerjes-Sanchez Carlos¹³,Koretsune Yukihiro¹⁴,Heuzey Jean-Yves Le¹⁵,Sawhney Jitendra PS¹⁶,Oh Seil¹⁷,Stępińska Janina¹⁸,Cate Vincent ten¹⁹,Verheugt Freek WA²⁰,Kayani Gloria²,Pieper Karen S²,Kakkar Ajay K²²¹,GARFIELD-AF investigators for the

Affiliation:

1. Department of Cardiology, University of Besançon, Besançon 25000, France

2. Department of Clinical Research, Thrombosis Research Institute, London SW3 6LR, UK

3. Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK

4. Department of Cardiology, Oslo University Hospital Ullevaal, Oslo PO Box 4956, Norway

5. Institute of Clinical Science, University of Oslo, Oslo PO Box 4956, Norway

6. Molecular & Clinical Sciences Research Institute, St George’s University of London, London SW17 0RE, UK

7. Department of Cardiology, AZ Klina, Brasschaat 100, 2930, Belgium

8. Department of Cardiology, Catholic University, Santiago 8330024, Chile

9. Centre for Cardiovascular Science, University of Edinburgh, Edinburgh EH16 4TJ, UK

10. Department of Medicine(Cardiology), Tokai University School of Medicine, Kanagawa 259-1143, Japan

11. Department of Medicine, Formerly Technical University of Munich, Munich 80333, Germany

12. Department of Neurology, University of Heidelberg, Heidelberg 69120, Germany

13. Instituto de Cardiologia y Medicina Vascular, Tec Salud, Garza Garcia 66278, Mexico

14. Institute for Clinical Research, Osaka National Hospital, Osaka 540-0006, Japan

15. Department of Arrhythmia, European Hospital Georges Pompidou, René Descartes University, Paris 75015, France

16. Department of Cardiology, Sir Ganga Ram Hospital, New Delhi 110060, India

17. Department of Internal Medicine, Seoul National University College of Medicine, Seoul 110-799, Republic of Korea

18. Intensive Cardiac Therapy Clinic, Institute of Cardiology, Warsaw 04-628, Poland

19. Cardiovascular Research Institute Maastricht, Maastricht 6200, The Netherlands

20. Depertment of Cardiology, Onze Lieve Vrouwe Gasthuis, Amsterdam NL-1091-AC, The Netherlands

21. Department of Surgery, University College London, London WC1E 6BT, UK

Abstract

The Global Anticoagulant Registry in the Field-Atrial Fibrillation (GARFIELD-AF) examined real-world practice in a total of 57,149 (5069 retrospective, 52,080 prospective) patients with newly diagnosed AF at risk of stroke/systemic embolism, enrolled at over 1000 centers in 35 countries. It aimed to capture data on AF burden, patients’ clinical profile, patterns of clinical practice and antithrombotic management, focusing on stroke/systemic embolism prevention, uptake of new oral anticoagulants, impact on death and bleeding. GARFIELD-AF set new standards for quality of data collection and analysis. A total of 36 peer-reviewed articles were already published and 73 abstracts presented at international congresses, covering treatment strategies, geographical variations in baseline risk and therapies, adverse outcomes and common comorbidities such as heart failure. A risk prediction tool as well as innovative observational studies and artificial intelligence methodologies are currently being developed by GARFIELD-AF researchers. Clinical Trial Registration: NCT01090362 (ClinicalTrials.gov).

Publisher

Future Medicine Ltd

Subject

Cardiology and Cardiovascular Medicine,Molecular Medicine

Link

https://www.futuremedicine.com/doi/pdf/10.2217/fca-2020-0014

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