1. Drug Resistance Unit, Section of Pharmacogenetics, Department of Physiology & Pharmacology, Karolinska Institutet, Stockholm, Sweden and Institute of Biotechnology & Bioengineering, Center of Molecular & Structural Biomedicine, University of Algarve, Faro, Portugal and Department of Biological Sciences, The Harpur College of Arts & Sciences, Binghamton University, Binghamton, NY, USA.