Do immune checkpoint inhibitors increase sensitivity to salvage chemotherapy?
Author:
Affiliation:
1. Hematology-Oncology Department, Faculty of medicine, Saint Joseph University, Beirut, Lebanon
Publisher
Future Medicine Ltd
Subject
Oncology,Immunology,Immunology and Allergy
Link
https://www.futuremedicine.com/doi/pdf/10.2217/imt-2017-0153
Reference16 articles.
1. Negative predictive biomarkers of checkpoint inhibitors in hyper-progressive tumors
2. Chemotherapeutics and Radiation Stimulate MHC Class I Expression through Elevated Interferon-beta Signaling in Breast Cancer Cells
3. Increased expression of CEA and MHC class I in colorectal cancer cell lines exposed to chemotherapy drugs
4. Gemcitabine Selectively Eliminates Splenic Gr-1+/CD11b+ Myeloid Suppressor Cells in Tumor-Bearing Animals and Enhances Antitumor Immune Activity
5. Chemotherapy Induces Programmed Cell Death-Ligand 1 Overexpression via the Nuclear Factor-κB to Foster an Immunosuppressive Tumor Microenvironment in Ovarian Cancer
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