Affiliation:
1. Department of Thoracic Oncology, National Cancer Center Hospital, Chuo-ku, Tokyo, Japan
Abstract
Lorlatinib, a third-generation ALK tyrosine kinase inhibitor, has been approved as a treatment for ALK-positive lung cancer. This review provides information regarding the pharmacology and clinical features of lorlatinib, including its efficacy and associated adverse events. Pivotal clinical trials are discussed along with the current status of lorlatinib as a treatment for ALK-positive lung cancer and future therapeutic challenges.
Subject
Cancer Research,Oncology,General Medicine
Cited by
8 articles.
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