Cancer and COVID-19: analysis of patient outcomes-Reference-Cited by-同舟云学术

Cancer and COVID-19: analysis of patient outcomes

Published:2021-09 Issue:26 Volume:17 Page:3499-3510
ISSN:1479-6694
Container-title:Future Oncology
language:en
Short-container-title:Future Oncology

Author:

Aboueshia Mohamed¹²^ORCID,Hussein Mohammad Hosny¹,Attia Abdallah S¹,Swinford Aubrey³,Miller Peter³,Omar Mahmoud¹,Toraih Eman Ali¹⁴^ORCID,Saba Nakhle⁵,Safah Hana⁵,Duchesne Juan⁶,Kandil Emad⁷

Affiliation:

1. Department of Surgery, Division of Endocrine & Oncologic Surgery, Tulane University, School of Medicine, New Orleans, LA 70112, USA

2. Department of Otolaryngology-Head & Neck Surgery, Faculty of Medicine, Suez Canal University, Ismailia, 41522, Egypt

3. Tulane University, School of Medicine, New Orleans, LA 70112, USA

4. Department of Histology & Cell Biology, Genetics Unit, Faculty of Medicine, Suez Canal University, Ismailia, 41522, Egypt

5. Section of Hematology & Medical Oncology, Deming Department of Medicine, Tulane University, New Orleans, LA 70112 USA

6. Trauma/Acute Care & Critical Care, Department of Surgery, Tulane, Tulane School of Medicine, New Orleans, LA 70112, USA

7. Department of Surgery, Tulane University School of Medicine, New Orleans, LA 70112 USA

Abstract

Background: We sought to investigate the outcomes associated with COVID-19 disease in cancer patients. Methods: We conducted a retrospective cohort study of laboratory-confirmed COVID-19 patients. Results: Of the 206 patients included, 57 had at least one preexisting malignancy. Cancer patients were older than noncancer patients. Of the 185 discharged cases, cancer patients had a significantly higher frequency of unplanned reintubation (7.1% vs 0.9%, p < 0.049), and required longer hospital stay (8.58 ± 6.50 days versus 12.83 ± 11.44 days, p < 0.002). Regression analysis revealed that obesity and active smoking were associated with an increased risk of mortality. Conclusion: Outcomes in COVID-19 appear to be driven by obesity as well as active smoking, with no difference in mortality between cancer and noncancer patients.

Publisher

Future Medicine Ltd

Subject

Cancer Research,Oncology,General Medicine

Link

https://www.futuremedicine.com/doi/pdf/10.2217/fon-2021-0121

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