Treatment patterns and economic burden among cervical and endometrial cancer patients newly initiating systemic therapy

Author:

Kebede Nehemiah1,Shah Ruchit1ORCID,Shah Anuj1,Corman Shelby1,Nwankwo Chizoba2

Affiliation:

1. Open Health Evidence & Access, Bethesda, MD 20814, USA

2. Merck & Co., Inc., Kenilworth, NJ 07033, USA

Abstract

Aim: To evaluate treatment patterns, healthcare resource use (HCRU) and all-cause healthcare costs among patients with cervical or endometrial cancer newly initiating systemic therapy. Methods: We identified patients with cervical or endometrial cancer newly initiating systemic therapy – a claims-based proxy for advanced disease – between 2014 and 2019, described them by line of therapy (LOT), and summarized the per patient per month (PPPM) HCRU and healthcare costs per LOT. Results: Among 1229 patients with cervical cancer and 2659 patients with endometrial cancer, LOT1 therapies included systemic only (cervical, 50.1%; endometrial, 83.2%) and systemic with radiation therapy (cervical, 49.9%; endometrial, 16.8%). Mean PPPM total costs were: LOT1 (cervical, US$15,892; endometrial, US$11,363), LOT2 (US$20,193; US$14,019) and LOT3+ (US$16,576; US$14,645). Conclusions: Overall, patients received guideline-concordant care and experienced significant economic burden, which increased with LOT.

Funder

Merck

Publisher

Future Medicine Ltd

Subject

Cancer Research,Oncology,General Medicine

Reference22 articles.

1. American Cancer Society. Cancer facts & figures 2019 (2019). www.cancer.org/cancer/cervical-cancer/about/key-statistics.html

2. American Cancer Society.Key Statistics for Cervical Cancer (2019). www.cancer.org/cancer/cervical-cancer/about/key-statistics.html

3. Demographic and insurance-based disparities in diagnosis of stage IV cervical cancer: A population-based analysis using NCDB.

4. Cervical Cancer, Version 3.2019, NCCN Clinical Practice Guidelines in Oncology

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