Molecular methods for increasing the effectiveness of ovarian cancer treatment: a systematic review

Author:

Chilimoniuk Zuzanna1ORCID,Rocka Agata1ORCID,Stefaniak Martyna1ORCID,Tomczyk Żaklina1ORCID,Jasielska Faustyna1ORCID,Madras Dominika1ORCID,Filip Agata2ORCID

Affiliation:

1. Students' Scientific Association at the Department of Cancer Genetics with Cytogenetics Laboratory, Medical University of Lublin, ul. Radziwiłłowska 11, Lublin, 20-080, Poland

2. Department of Cancer Genetics with Cytogenetics Laboratory, Medical University of Lublin, ul. Radziwiłłowska 11, Lublin, 20-080, Poland

Abstract

Background: The aim of the current study is to analyze and summarize the latest research on improving therapy in ovarian cancer. Materials & methods: Data analysis was based on a review of publications from 2011 to 2021 in the PubMed database with use of the search terms including ‘EGFR ovarian cancer’, ‘folate receptor inhibitors ovarian cancer’, ‘VEGF ovarian cancer’, ‘PDGF ovarian cancer’ and ‘CTLA-4 ovarian cancer’. Results: 6643 articles were found; 238 clinical trials and randomized control trials were analyzed; 122 studies were rejected due to inconsistency with the topic of the work. Conclusion: Extensive research on the treatment of ovarian cancer increases the chance of developing the most effective therapy suited to the individual needs of the patient.

Publisher

Future Medicine Ltd

Subject

Cancer Research,Oncology,General Medicine

Reference185 articles.

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