Trifluridine/tipiracil in the treatment of gastric cancer
Author:
Affiliation:
1. Drug Development Unit, Sarah Cannon Research Institute UK, 93 Harley Street, Marylebone, W1G 6AD, London, United Kingdom
2. Cancer Institute, University College London, 72 Huntley Street, Bloomsbury, WC1E 6DD, London, United Kingdom
Abstract
Publisher
Future Medicine Ltd
Subject
Cancer Research,Oncology,General Medicine
Link
https://www.futuremedicine.com/doi/pdf/10.2217/fon-2021-0754
Reference24 articles.
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2. Trifluridine/tipiracil: an emerging strategy for the management of gastrointestinal cancers
3. Taiho Oncology, Inc. Announces FDA Approval of LONSURF® (trifluridine and tipiracil) for refractory metastatic colorectal cancer (mCRC). www.taihooncology.com/documents/32/lon-pm-us-0270-taiho-oncology-lonsurf_fda-approval-press-release_sept-22_final.pdf
4. A phase 1 study of the pharmacokinetics of nucleoside analog trifluridine and thymidine phosphorylase inhibitor tipiracil (components of TAS-102) vs trifluridine alone
5. TAS-102: A resurrected novel Fluoropyrimidine with expanding role in the treatment of gastrointestinal malignancies
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1. Applicable Pharmacokinetic Study: Development and Validation of Bioanalytical LC-MS/MS Method for Simultaneous Determination of Tipiracil, Trifluridine and Its Two Metabolites 5-Trifluoromethyluracil, 5-Carboxy 2′-Deoxyuridine in Rat Plasma;Separations;2023-12-26
2. A guide for the synthesis of key nucleoside scaffolds in drug discovery;Medicinal Chemistry Research;2023-06-20
3. Recent Trends and Advancements in the Diagnosis and Management of Gastric Cancer;Cancers;2022-11-15
4. Novel pyrrolidine-aminophenyl-1,4-naphthoquinones: structure-related mechanisms of leukemia cell death;Molecular and Cellular Biochemistry;2022-07-14
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