National Early Warning Score 2 and laboratory predictors correlate with clinical deterioration in hospitalized patients with COVID-19-Reference-Cited by-同舟云学术

National Early Warning Score 2 and laboratory predictors correlate with clinical deterioration in hospitalized patients with COVID-19

Published:2021-08 Issue:11 Volume:15 Page:807-820
ISSN:1752-0363
Container-title:Biomarkers in Medicine
language:en
Short-container-title:Biomarkers in Medicine

Author:

Tuncer Gulsah¹^ORCID,Surme Serkan¹^ORCID,Bayramlar Osman F²^ORCID,Karanalbant Hatice K¹^ORCID,Copur Betul¹^ORCID,Yazla Meltem¹^ORCID,Zerdali Esra¹^ORCID,Nakir Inci Y¹^ORCID,Cinar Ayse RK¹^ORCID,Buyukyazgan Ahmet¹^ORCID,Balli Hatice¹^ORCID,Kurekci Yesim¹^ORCID,Simsek-Yavuz Serap³^ORCID,Sonmez Mehmet M⁴^ORCID,Sengoz Gonul¹^ORCID,Pehlivanoglu Filiz¹^ORCID

Affiliation:

1. Department of Infectious Diseases & Clinical Microbiology, Haseki Training & Research Hospital, Istanbul, Turkey

2. Department of Public Health, Bakirkoy District Health Directorate, Istanbul, Turkey

3. Department of Infectious Diseases & Clinical Microbiology, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey

4. Department of Orthopaedic Surgery & Traumatology, Haseki Training & Research Hospital, Istanbul, Turkey

Abstract

Aim: We aimed to determine the prognostic values of the National Early Warning Score 2 (NEWS2) and laboratory parameters during the first week of COVID-19. Materials & methods: All adult patients who were hospitalized for confirmed COVID-19 between 11 March and 11 May 2020 were retrospectively included. Results: Overall, 611 patients were included. Our results showed that NEWS2, procalcitonin, neutrophil/lymphocyte ratio and albumin at D0, D3, D5 and D7 were the best predictors for clinical deterioration defined as a composite of ICU admission during hospitalization or in-hospital death. Procalcitonin had the highest odds ratio for clinical deterioration on all days. Conclusion: This study provides a list of several laboratory parameters correlated with NEWS2 and potential predictors for clinical deterioration in patients with COVID-19.

Publisher

Future Medicine Ltd

Subject

Biochemistry (medical),Clinical Biochemistry,Drug Discovery

Link

https://www.futuremedicine.com/doi/pdf/10.2217/bmm-2021-0061

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