Prognostic value of triglyceride/glucose index in patients with ST-segment elevation myocardial infarction

Author:

Özkalaycı Flora1,Karagöz Ali2,Karabay Can Y3,Tanboga İbrahim H14,Türkyılmaz Erdem5,Saygı Mehmet1,Oduncu Vecih6

Affiliation:

1. Department of Cardiology, Hisar Intercontinental Hospital, İstanbul, Turkey

2. Department of Cardiology, Kartal Kosuyolu Training & Research Hospital, İstanbul, Turkey

3. Department of Cardiology, University of Health Science Siyami Ersek, Training & Research Hospital, İstanbul, Turkey

4. Department of Biostatistics & Cardiology, Nişantasi University, School of Medicine, İstanbul, Turkey

5. Department of Cardiology, Uşak State Hospital, Turkey

6. Department of Cardiology, Bahcesehir University, School of Medicine, İstanbul, Turkey

Abstract

Aim: New parameters are emerging to predict prognosis in patients with ST-segment elevation myocardial infarction (STEMI). In this study we aimed to determine and compare the prognostic values of some metabolic indices in terms of predicting long-term mortality in patients with STEMI. Method: A total of 1900 nondiabetic patients who presented with STEMI and underwent percutaneous coronary intervention were included in the study. Multivariable Cox proportional regression analysis was used to determine and compare the predictive performance of triglyceride–glucose (TyG) index, triglyceride–high-density lipoprotein ratio (Ty/HDL) and admission glucose. Results: In multivariable Cox regression analysis, the model based on TyG index had better predictive performance than the Ty/HDL and admission blood glucose. Conclusion: The TyG index is more informative than Ty/HDL and admission glucose level to predict long-term all-cause mortality.

Publisher

Future Medicine Ltd

Subject

Biochemistry (medical),Clinical Biochemistry,Drug Discovery

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