Genetics and imaging of oligodendroglial tumors-Reference-Cited by-同舟云学术

Genetics and imaging of oligodendroglial tumors

Published:2015-10 Issue:5 Volume:4 Page:307-315
ISSN:2045-0907
Container-title:CNS Oncology
language:en
Short-container-title:CNS Oncology

Author:

Ellenbogen Jonathan R¹,Walker Carol¹,Jenkinson Michael D¹²

Affiliation:

1. Department of Neurosurgery, The Walton Centre NHS Foundation Trust, Lower Lane, Liverpool, L9 7LJ, UK

2. Institute of Translational Medicine, University of Liverpool, Clinical Science Centre, Liverpool, L9 7LJ, UK

Abstract

Oligodendroglial tumors are chemosensitive with a favorable prognosis compared with other histological subtypes. The genetic hallmark of co-deletion of 1p and 19q determines both treatment response and prognosis. While this test now forms part of routine histopathology diagnosis in many laboratories, alternative noninvasive imaging biomarkers of tumor genotype remain an attractive proposition. This review will focus on imaging biomarkers of molecular genetics in oligodendroglial tumors.

Publisher

Future Medicine Ltd

Subject

General Medicine

Link

https://www.futuremedicine.com/doi/pdf/10.2217/cns.15.37

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