Integrated in a systems pharmacology approach, pharmacogenetics holds the promise for personalized medicine in neonates-Reference-Cited by-同舟云学术

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Integrated in a systems pharmacology approach, pharmacogenetics holds the promise for personalized medicine in neonates

Published:2022-08 Issue:12 Volume:23 Page:667-670
ISSN:1462-2416
Container-title:Pharmacogenomics
language:en
Short-container-title:Pharmacogenomics

Author:

Allegaert Karel¹²³⁴^ORCID

Affiliation:

1. Department of Pharmaceutical & Pharmacological Sciences, KU Leuven, Leuven, Belgium

2. Department of Development & Regeneration, KU Leuven, Leuven, Belgium

3. Leuven Child & Youth Institute, KU Leuven, Leuven, Belgium

4. Department of Hospital Pharmacy, Erasmus MC, Rotterdam, The Netherlands

Abstract

Tweetable abstract Integrated in a systems pharmacology approach, pharmacogenetics holds the promise for personalized medicine in neonates. This has been illustrated for some diseases specific to neonates.

Publisher

Future Medicine Ltd

Subject

Pharmacology,Genetics,Molecular Medicine

Link

https://www.futuremedicine.com/doi/pdf/10.2217/pgs-2022-0100

Reference16 articles.

1. Neonatal drug therapy: The first frontier of therapeutics for children

2. Genetics of neonatal-onset epilepsies

3. Non-maturational covariates for dynamic systems pharmacology models in neonates, infants, and children: Filling the gaps beyond developmental pharmacology

4. Ontogeny of Hepatic Transporters and Drug-Metabolizing Enzymes in Humans and in Nonclinical Species

5. Approaches to Dose Finding in Neonates, Illustrating the Variability between Neonatal Drug Development Programs

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