Surgical management of the patient with primary hyperparathyroidism

Abstract

Abstract:  The successful surgical management of primary hyperparathyroidism requires a surgeon with a clear understanding of both the embryology and anatomy of the parathyroid glands. While the majority of patients may only have a single diseased gland, there is no 100% confirmation that can be attained in the preoperative period. For this reason, even when imaging is suggestive of a single diseased gland, additional intraoperative adjuncts should be used. Intraoperative parathyroid hormone monitoring is the most commonly used adjunct. When preoperative localization is not possible, or intraoperative parathyroid hormone levels fail to meet criteria for successful resection, the patient requires a four gland exploration. Cure is not confirmed until normocalcemia is documented for at least 6 months after surgery.