An assessment of co-contraction in reinnervated muscle

Author:

Wilcox Matthew123,Brown Hazel12,Johnson Kathryn1,Sinisi Marco1,Quick Tom J12

Affiliation:

1. Peripheral Nerve Injury Research Unit, Royal National Orthopaedic Hospital, London, HA7 4LP, UK

2. University College London Centre for Nerve Engineering, London, WC1E 6BT, UK

3. Department of Pharmacology, University College London, School of Pharmacy, London, WC1N 1AX, UK

Abstract

Aim: To investigate co-contraction in reinnervated elbow flexor muscles following a nerve transfer. Materials & methods: 12 brachial plexus injury patients who received a nerve transfer to reanimate elbow flexion were included in this study. Surface electromyography (EMG) recordings were used to quantify co-contraction during sustained and repeated isometric contractions of reinnervated and contralateral uninjured elbow flexor muscles. Reuslts: For the first time, this study reveals reinnervated muscles demonstrated a trend toward higher co-contraction ratios when compared with uninjured muscle and this is correlated with an earlier onset of muscle fatigability. Conclusion: Measurements of co-contraction should be considered within muscular function assessments to help drive improvements in motor recovery therapies.

Funder

Royal National Orthopaedic Hospital Charitable Trust

UCL Graduate Research Scholarship

Publisher

Future Medicine Ltd

Subject

Embryology,Biomedical Engineering

Reference60 articles.

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