Oral status and periodontal microbiota of HIV-infected youth infected by vertical transmission-Reference-Cited by-同舟云学术

Oral status and periodontal microbiota of HIV-infected youth infected by vertical transmission

Published:2018-04-01 Issue:4 Volume:13 Page:275-285
ISSN:1746-0794
Container-title:Future Virology
language:en
Short-container-title:Future Virology

Author:

Ferreira Mariana VM¹²,Cavalcanti Édila FF¹,PM Rubini Norma de³,Ferreira Dennis C⁴,Gonçalves Lucio S⁴,V Colombo Ana Paula²

Affiliation:

1. School of Dentistry, Department of Clinics, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil

2. Department of Medical Microbiology, Institute of Microbiology, Federal University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil

3. Department of Allergy & Immunology, Gafrée e Guinle University Hospital, Federal University of the State of Rio de Janeiro, Rio de Janeiro, RJ, Brazil

4. School of Dentistry, Estácio de Sá University, Rio de Janeiro, RJ, Brazil

Abstract

Aim: This study evaluated the oral status and microbiota of HIV+ youth infected by vertical transmission. Materials & methods: 34 HIV+ and 36 HIV- individuals (14–24 years of age) were examined for oral infections/lesions. Subgingival biofilm was collected and the microbiota determined by checkerboard DNA–DNA hybridization. Results: Over 90% of the HIV+ youth were under highly active antiretroviral therapy, but 64.6% had AIDS and 47% presented oral manifestations. HIV+ youth showed more periodontal attachment loss and inflammation than HIV- (p < 0.05), and also high prevalence of caries. Most species were detected in higher prevalence in the microbiota of HIV+ than controls. Conclusion: HIV+ youth infected by vertical transmission presented more periodontal destruction and inflammation, and greater prevalence of microbial pathogens compared with HIV- individuals.

Publisher

Future Medicine Ltd

Subject

Virology

Link

https://www.futuremedicine.com/doi/pdf/10.2217/fvl-2018-0025

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