HIV-1 subtype diversity, transmitted drug resistance and phylogenetics in Australia

Author:

Pinto Angie N1,Hawke Karen2,Castley Allison3,Chibo Doris4,Giallonardo Francesca Di1,Cooper Craig5,Sawleshwarkar Shailendra6,Kelleher Anthony1,Dwyer Dominic E78

Affiliation:

1. The Kirby Institute, The University of New South Wales, UNSW Sydney, Australia

2. South Australian Health & Medical Research Institute, Adelaide, South Australia

3. PathWest, Clinical Immunology, Department of Health, Murdoch, Western Australia, Australia

4. HIV Characterization Laboratory, Victorian Infectious Diseases Reference Laboratory, Doherty Institute, Melbourne, Victoria, Australia

5. Positive Life NSW, Sydney, New South Wales, Australia

6. The University of Sydney, Faculty of Medicine & Health, Westmead Clinical School, Western Sydney Sexual Health Centre, Parramatta, New South Wales, Australia

7. NSWHP-ICPMR, Westmead Hospital, Westmead, NSW, Australia

8. Westmead Clinical School, University of Sydney, Westmead, Australia

Abstract

Australia has maintained a low prevalence of HIV, with a mainly concentrated epidemic and successful public health response. With the widespread availability of HIV genotyping for resistance testing, and development of phylogenetic methodologies, the field of molecular epidemiology has evolved a deeper understanding of diversity and transmission dynamics of HIV. Studies combining HIV genotype with epidemiological data have allowed insights to be gained into the changing subtype diversity, rates of transmitted drug resistance and transmission networks of HIV in Australia. This review provides an overview of HIV molecular epidemiology studies in Australia.

Publisher

Future Medicine Ltd

Subject

Virology

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5. The Kirby Institute. Annual surveillance report of HIV, viral hepatitis, STIs 2017 (2017). https://kirby.unsw.edu.au/report/annual-surveillance-report-hiv-viral-hepatitis-and-stis-australia-2017.

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