Nano drug-delivery systems for management of AIDS: liposomes, dendrimers, gold and silver nanoparticles-Reference-Cited by-同舟云学术

Nano drug-delivery systems for management of AIDS: liposomes, dendrimers, gold and silver nanoparticles

Published:2023-02 Issue:3 Volume:18 Page:279-302
ISSN:1743-5889
Container-title:Nanomedicine
language:en
Short-container-title:Nanomedicine

Author:

Asl Fateme Davarani¹^ORCID,Mousazadeh Marziyeh²^ORCID,Taji Shirinsadat²³^ORCID,Bahmani Abbas⁴,Khashayar Patricia⁵,Azimzadeh Mostafa⁶^ORCID,Mostafavi Ebrahim⁷⁸^ORCID

Affiliation:

1. Department of Medical Biotechnology, School of Advanced Technologies, Shahrekord University of Medical Sciences, Shahrekord, 88138-33435, Iran

2. Department of Nanobiotechnology, Faculty of Biological Sciences, Tarbiat Modares University, Tehran, 14115-154, Iran

3. Institute for Genetics, University of Cologne, Cologne, D-50674, Germany

4. Institute for Nanoscience & Nanotechnology (INST), Sharif University of Technology, Tehran, 14588-89694, Iran

5. Center for Microsystems Technology, Imec & Ghent University, Ghent, 9050, Belgium

6. Medical Nanotechnology & Tissue Engineering Research Center, Yazd Reproductive Sciences Institute, Shahid Sadoughi University of Medical Sciences, Yazd, 89195-999, Iran

7. Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA 94305, USA

8. Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA

Abstract

AIDS causes increasing mortality every year. With advancements in nanomedicine, different nanomaterials (NMs) have been applied to treat AIDS and overcome its limitations. Among different NMs, nanoparticles (NPs) can act as nanocarriers due to their enhanced solubility, sustained release, targeting abilities and facilitation of drug–dose reductions. This review discusses recent advancements in therapeutics for AIDS/HIV using various NMs, mainly focused on three classifications: polymeric, liposomal and inorganic NMs. Polymeric dendrimers, polyethylenimine-NPs, poly(lactic-co-glycolic acid)-NPs, chitosan and the use of liposomal-based delivery systems and inorganic NPs, including gold and silver NPs, are explored. Recent advances, current challenges and future perspectives on the use of these NMs for better management of HIV/AIDS are also discussed.

Publisher

Future Medicine Ltd

Subject

Development,General Materials Science,Biomedical Engineering,Medicine (miscellaneous),Bioengineering

Link

https://www.futuremedicine.com/doi/pdf/10.2217/nnm-2022-0248

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