Part I: recent developments in nanoelectrodes for biological measurements

Author:

Shi Haibin1,Yeh Joanne I12

Affiliation:

1. University of Pittsburgh Medical School, Department of Structural Biology, 3501 5th Avenue, BST3 1036, Pittsburgh, PA 15260, USA

2. University of Pittsburgh Medical School, Department of Bioengineering, 3501 5th Avenue, BST3 1036, Pittsburgh, PA 15260, USA.

Abstract

Biosensors are a type of analytical device that use biological molecules to monitor biorecognition events and interactions. Coupled with the progress in nanotechnologies over recent years, the development of a nanobiosensor based on individual nanoelectrodes and nanoelectrode arrays or nanoelectrode ensembles offers unprecedented avenues for screening and detection at ultrahigh sensitivities. These capabilities provide the basis for a paradigmatic change in biomedical diagnostics and treatment. In this review, we highlight recent developments in nanoelectrode platforms and their suitability for integrating with biological components for the fabrication of ultrasensitive nanobiosensors.

Publisher

Future Medicine Ltd

Subject

Development,General Materials Science,Biomedical Engineering,Medicine (miscellaneous),Bioengineering

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