Time to open the blood–brain barrier gate for biologics?
Author:
Affiliation:
1. Pharma Research & Early Development (pRED), Neuroscience Discovery and Translation Area, F Hoffmann-La Roche, Basel, Switzerland
2. Pharma Research & Early Development (pRED), Large Molecule Research, F Hoffmann-La Roche, Penzberg, Germany
Publisher
Future Medicine Ltd
Subject
Neurology (clinical),Neurology
Link
https://www.futuremedicine.com/doi/pdf/10.2217/fnl.14.15
Reference18 articles.
1. Monoclonal antibody therapeutics: history and future
2. Receptor-Mediated Peptide Transport through the Blood-Brain Barrier*
3. Anti-transferrin receptor antibody and antibody-drug conjugates cross the blood-brain barrier.
4. Molecular Trojan horses for blood–brain barrier drug delivery
Cited by 11 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Next Generation of Brain Cancer Nanomedicines to Overcome the Blood–Brain Barrier (BBB): Insights on Transcytosis, Perivascular Tumor Growth, and BBB Models;Advanced Therapeutics;2023-09-24
2. Approaches Towards Prediction of CNS PK and PD;Drug Delivery to the Brain;2022
3. Brain pharmacokinetics of anti-transferrin receptor antibody affinity variants in rats determined using microdialysis;mAbs;2021-01-01
4. Tetravalent Bispecific Tandem Antibodies Improve Brain Exposure and Efficacy in an Amyloid Transgenic Mouse Model;Molecular Therapy - Methods & Clinical Development;2020-12
5. Targeting the transferrin receptor for brain drug delivery;Progress in Neurobiology;2019-10
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3