Biological imaging for individualized therapy in radiation oncology: part II medical and clinical aspects

Author:

Gkika Eleni12,Oehlke Oliver12,Bunea Hatice12,Wiedenmann Nicole12,Adebahr Sonja12,Nestle Ursula12,Zamboglou Constantinos12,Kirste Simon12,Fennell Jamina12,Brunner Thomas12,Gainey Mark12,Baltas Dimos12,Langer Mathias3,Urbach Horst4,Bock Michael5,Meyer Philipp T26,Grosu Anca-Ligia12

Affiliation:

1. Department of Radiation Oncology, Medical Center, Faculty of Medicine, University of Freiburg, D-79106, Germany

2. German Cancer Consortium (DKTK), Partner Site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, D-69120, Germany

3. Department of Radiology, Medical Center, Faculty of Medicine, University of Freiburg, D-79106, Germany

4. Department of Neuroradiology, Medical Center, Faculty of Medicine, University of Freiburg, D-79106, Germany

5. Department of Radiology – Medical Physics, Department of Radiology, Faculty of Medicine, Medical Center, University of Freiburg, D-79106, Germany

6. Department of Nuclear Medicine, Medical Center, Faculty of Medicine, University of Freiburg, D-79106, Germany

Abstract

Positron emission tomography and multiparametric MRI provide crucial information concerning tumor extent and normal tissue anatomy. Moreover, they are able to visualize biological characteristics of the tumor, which can be considered in the radiation treatment planning and monitoring. In this review we discuss the impact of biological imaging positron emission tomography and multiparametric MRI for radiation oncology, based on the data of the literature and on the experience of our own institution in this field.

Publisher

Future Medicine Ltd

Subject

Cancer Research,Oncology,General Medicine

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