High-frequency oscillations and other electrophysiological biomarkers of epilepsy: clinical studies-Reference-Cited by-同舟云学术

High-frequency oscillations and other electrophysiological biomarkers of epilepsy: clinical studies

Published:2011-10 Issue:5 Volume:5 Page:557-566
ISSN:1752-0363
Container-title:Biomarkers in Medicine
language:en
Short-container-title:Biomarkers in Medicine

Author:

Worrell Greg¹,Gotman Jean²

Affiliation:

1. Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.

2. Montreal Neurological Institute, Montreal, Québec, Canada

Abstract

Accurate localization of epileptogenic brain is critical for successful epilepsy surgery. Recent research using wide bandwidth intracranial EEG has demonstrated that interictal high-frequency oscillations are preferentially localized to the brain region generating spontaneous seizures, and are a potential biomarker of epileptogenic brain. The existence of an interictal, electrophysiological biomarker of epileptogenic brain has the potential to significantly advance epilepsy surgery by improving outcomes through improved localization and potentially eliminating the reliance on chronic intracranial EEG monitoring.

Publisher

Future Medicine Ltd

Subject

Biochemistry, medical,Clinical Biochemistry,Drug Discovery

Link

https://www.futuremedicine.com/doi/pdf/10.2217/bmm.11.74

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