High serum levels of ferritin may predict poor survival and walking ability for patients with hip fractures: a propensity score matching study

Author:

Liu Mingchong1ORCID,Yang Chensong1,Chu Qining2,Wang Jiansong1,Wang Qidong1,Kong Fanyu1,Sun Guixin1

Affiliation:

1. Department of Traumatic Surgery, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, 200092, China

2. Emergency Trauma Center, Nanyang Second General Hospital, No 66, East Jianshe Road, Nanyang, 473000, China

Abstract

Aim: To identify the relationship between ferritin and outcomes for patients with hip fractures. Patients & methods: All patients with hip fractures presenting between May 2017 and January 2021 were included. Univariate and multivariate analyses were performed to determine the risk factors for 1-year survival. Propensity score matching (PSM) was performed for groups divided by ferritin levels. Results: A total of 165 patients were included of whom 28 died during the first year after surgery. Ferritin levels differed significantly between groups divided by 1-year survival. High ferritin (≥308.5 ng/ml) was related to poor 1-year survival and 6-month and 1-year independent walking rate. Conclusion: High ferritin (≥308.5 ng/ml) may predict poor survival and free-walking abilities after surgery for patients with hip fractures.

Funder

National Natural Science Foundation of China

Scientific and Technological Innovation Action Program of Shanghai Science and Technology Commission

Publisher

Future Medicine Ltd

Subject

Biochemistry (medical),Clinical Biochemistry,Drug Discovery

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