Novel marker for predicting the severity and prognosis of acute pulmonary embolism: platelet-to-hemoglobin ratio

Author:

Ozbeyaz Nail B1ORCID,Gokalp Gokhan1ORCID,Gezer Adil E2ORCID,Algul Engin3ORCID,Sahan Haluk F3ORCID,Aydinyilmaz Faruk4ORCID,Guliyev Ilkin5ORCID,Kalkan Kamuran3ORCID

Affiliation:

1. Department of Cardiology, Pursaklar State Hospital, Ankara, 06145, Turkey

2. Department of Emergency Medicine, Pursaklar State Hospital, Ankara, 06145, Turkey

3. Department of Cardiology, Diskapi Yildirim Beyazit Training & Research Hospital, University of Health Sciences, Ankara, 06145, Turkey

4. Department of Cardiology, Erzurum Education & Research Hospital, Erzurum, 25030, Turkey

5. Department of Cardiology, Medical Park Hospital, Tokat, 60235, Turkey

Abstract

Background: We investigated the ability of the platelet-to-hemoglobin ratio (PHR) to predict mortality and disease severity in patients with acute pulmonary embolism (APE). Materials & methods: The severity of APE was classified as massive (high risk), submassive (intermediate risk) or nonmassive (low risk). PHR is defined as platelet count/hemoglobin count. Results: PHR was significantly higher in patients with massive APE, and this elevation showed a gradual increase from the nonmassive group to the massive group (p < 0.001). In-hospital and 1-month mortality were higher in patients with high PHR values. PHR was an independent risk factor for the development of massive APE (odds ratio: 1.014; 95% CI: 1.011–1.017; p = 0.009). Conclusion: PHR values predicted massive APE and were an independent predictor of mortality in APE.

Publisher

Future Medicine Ltd

Subject

Biochemistry (medical),Clinical Biochemistry,Drug Discovery

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