Meningitis patients with pneumonia: correlation between blood parameters and clinical features

Author:

Lu Liuyi1ORCID,Li Taijie2,Chen Huaping1,Zhang Linyan1,Chen Mingxing1,Peng Qiliu3,Qin Xue1ORCID

Affiliation:

1. Department of Clinical Laboratory, First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, Guangxi, China

2. Department of Laboratory Medicine, Wuming Hospital of Guangxi Medical University, Nanning, 530199, Guangxi, China

3. Department of Clinical Laboratory, Guangxi International Zhuang Medicine Hospital, Nanning, 530201, Guangxi, China

Abstract

Background: This research aimed to explore the possible relationship between the main experimental parameters and clinical status in meningitis patients with pneumonia infection. Methods: A retrospective analysis of the demographic characteristics, clinical features and laboratory parameters of meningitis patients was performed. Results: D-dimer, C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR) exhibited good diagnostic ability for meningitis complicated with pneumonia. Additionally, we observed a positive correlation between D-dimer and CRP in cases of meningitis with pneumonia infection. D-dimer, ESR and Streptococcus pneumoniae ( S. pneumoniae) were independently associated with meningitis patients with pneumonia infection. Conclusion: D-dimer, CRP, ESR and S. pneumoniae infection may effectively anticipate disease progression and adverse consequences in meningitis patients with pneumonia infection.

Funder

Doctoral Research Fund of Guangxi University of Chinese Medicine

Publisher

Future Medicine Ltd

Subject

Biochemistry (medical),Clinical Biochemistry,Drug Discovery

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