Biomaterials and stem cells as drug/gene-delivery vehicles for Parkinson's treatment: an update-Reference-Cited by-同舟云学术

Biomaterials and stem cells as drug/gene-delivery vehicles for Parkinson's treatment: an update

Published:2021-12 Issue:12 Volume:16 Page:1057-1072
ISSN:1746-0751
Container-title:Regenerative Medicine
language:en
Short-container-title:Regenerative Medicine

Author:

Roshani Milad¹²,Kiaie Nasim³,Aghdam Rouhollah Mehdinavaz¹

Affiliation:

1. School of Metallurgy & Materials Engineering, College of Engineering, University of Tehran, Tehran 11155-4563, Iran

2. Department of Biomedical Engineering, Shahab Danesh University, Qom, Iran

3. Research Center for Advanced Technologies in Cardiovascular Medicine, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran

Abstract

By introducing biomaterials and stem cells into Parkinson’s disease (PD), therapeutic approaches have led to promising results due to facilitating brain targeting and blood–brain barrier permeation of the drugs and genes. Here, after reviewing the most recent drug- and gene-delivery vehicles including liposomes, exosomes, natural/synthetic polymeric particles/fibers, metallic/ceramic nanoparticles and microbubbles, used for Parkinson’s disease treatment, the effect of stem cells as a reservoir of neurotrophic factors and exosomes is provided.

Publisher

Future Medicine Ltd

Subject

Embryology,Biomedical Engineering

Link

https://www.futuremedicine.com/doi/pdf/10.2217/rme-2021-0050

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