Indications and limitations of endoscopic skull base surgery

Abstract

A wealth of critical neurovascular structures within a relatively small surface area adds to the already intricate nature of skull base surgery. Surgical approaches to the area are difficult and often associated with significant morbidity and mortality. During the past two decades, endoscopic endonasal approaches (EEAs) have evolved to access the ventral skull base for the resection of tumors (benign and malignant), the decompression of neural structures including the cervicomedullary junction (pannus from rheumatoid arthritis or congenital anomalies, such as platybasia) and the reconstruction of skull base defects (cerebrospinal leaks, meningoencephalocele). These minimal access approaches obviate the need for external incisions, translocation of maxillofacial bones and retraction of the brain. Furthermore, EEAs yield improved visualization, which may reduce complications, and improve quality of life outcomes. Anatomical difficulties (e.g., vascular encasement or extension beyond the plane of a major vessel or cranial nerve), various special conditions (e.g., pediatric patients and vascular tumor) and limitation of institutional resources and technical difficulties may limit the use of EEAs. Thus, one should understand the indications and limitations of EEAs to optimize patient selection, which, in turn, may lead to superior surgical outcomes and reduced morbidity.