The CorMatrix Cor™ PATCH for epicardial infarct repair

Author:

Vasanthan Vishnu1,Biglioli Matteo1,Hassanabad Ali Fatehi1,Dundas Jameson1,Matheny Robert G2,Fedak Paul WM1ORCID

Affiliation:

1. Department of Cardiac Sciences, Section of Cardiac Surgery, Libin Cardiovascular Institute, Cumming School of Medicine, University of Calgary, AB, T2N 4N1, Canada

2. Cormatrix Cardiovascular Inc., Roswell, GA 30076, USA

Abstract

Contemporary management of ischemic heart disease lacks strategies to directly access the heart and promote reparative cellular mechanisms to improve postinfarct cardiac remodeling. Epicardial infarct repair (EIR) is an emerging technique whereby bioactive materials are sewn over ischemic areas of the heart at the time of surgical revascularization to promote adaptive cardiac repair. The CorMatrix Cor™ PATCH (CorMatrix Cardiovascular Inc., GA, USA) is an acellular bioactive material compatible with EIR. Herein, we review current preclinical and clinical data for the CorMatrix Cor PATCH and its use in EIR.

Publisher

Future Medicine Ltd

Subject

Cardiology and Cardiovascular Medicine,Molecular Medicine

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