Computed tomography coronary angiography as the noninvasive in stable coronary artery disease? Long-term outcomes meta-analysis-Reference-Cited by-同舟云学术

Computed tomography coronary angiography as the noninvasive in stable coronary artery disease? Long-term outcomes meta-analysis

Published:2022-05 Issue:5 Volume:18 Page:407-416
ISSN:1479-6678
Container-title:Future Cardiology
language:en
Short-container-title:Future Cardiology

Author:

De Campos Diana¹^ORCID,Teixeira Rogério¹²,Saleiro Carolina¹,Lopes João¹,Botelho Ana¹,Gonçalves Lino¹²

Affiliation:

1. Centro Hospitalar e Universitário de Coimbra - Hospital Geral, Quinta dos Vales, São Martinho do Bispo 108, 3041-801, Coimbra, Portugal

2. Faculdade de Medicina da Universidade de Coimbra, R. Larga 2, 3000-370, Coimbra, Portugal

Abstract

Aim: To compare outcomes of coronary computed tomography angiography (CCTA) with that of functional testing (FT) in stable coronary artery disease. Methods: We searched PubMed, Embase, and Cochrane for randomized controlled trials (RCTs). A random-effects meta-analysis targeting all-cause death and nonfatal acute coronary syndromes was performed. Results: Eight RCTs enrolling 29,579 patients were included. Pooled relative risk (RR) for the primary end point was similar between CCTA and FT (RR = 0.97; 95% CI: 0.76–1.22). CCTA outperformed FT in nonfatal myocardial infarction (MI) (RR = 0.59; 95% CI: 0.41–0.83) and in downstream testing (OR: 0.47; 95% CI: 0.21–1.01). Conclusion: Updated data of stable coronary artery disease suggests that CCTA improved nonfatal MI and downstream testing.

Publisher

Future Medicine Ltd

Subject

Cardiology and Cardiovascular Medicine,Molecular Medicine

Link

https://www.futuremedicine.com/doi/pdf/10.2217/fca-2021-0103

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