Outcomes in cardiac implantable electronic device-related infective endocarditis: a systematic review of current literature

Author:

Sanghavi Ria1ORCID,Ravikumar Nidhruv2ORCID,Sarodaya Varun3ORCID,Haq Mawiyah4ORCID,Sherif Mohamed5,Harky Amer6ORCID

Affiliation:

1. Department of Medical Sciences, College of Life Sciences, University Of Leicester, Leicester, UK

2. Department of Medicine, School of Medicine, Queen’s University Belfast, Belfast, UK

3. Department of General Surgery, Junior Clinical fellow, Barts Health NHS Trust, London, UK

4. Faculty of Medicine, St George’s University of London, London, UK

5. Department of Cardiothoracic Surgery, Northern General Hospital, Sheffield, UK

6. Department of Cardiothoracic Surgery, Liverpool Heart & Chest Hospital, Liverpool, UK

Abstract

Aim: Cardiac implantable electronic device infective endocarditis is a serious infection with poor prognosis. Materials & methods: The systematic review of the literature was conducted using searches from the various databases. We included studies published between January 2010 and June 2021. Results: A total of 35 articles met the inclusion criteria. Patients were approximately 70 years old and an average of 71.2% of patients were male. The most common presenting feature was a fever. The modified Duke criteria was used to aid diagnosis. Management entailed extraction of the cardiac implantable electronic device in 80.5% of the studies. The overall mortality rates ranged from 4 to 36%. The most frequently isolated organism was Staphylococcus aureus. Conclusion: Cardiac implantable electronic device infective endocarditis needs timely diagnosis and effective management for promising outcomes.

Publisher

Future Medicine Ltd

Subject

Cardiology and Cardiovascular Medicine,Molecular Medicine

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