Respect the anaerobic nature of stem cells to exploit their potential in regenerative medicine
Author:
Affiliation:
1. Aquitaine-Limousin Branch of French Blood Institute, Place Amélie Raba Léon CS21010, Bordeaux 33075, France and UMR5164, CNRS/Bordeaux Segalen University, 146 rue Léo Saignat, Bâtiment AB, 33076 Bordeaux, France.
Publisher
Future Medicine Ltd
Subject
Embryology,Biomedical Engineering
Link
https://www.futuremedicine.com/doi/pdf/10.2217/rme.13.65
Reference31 articles.
1. The role of hypoxia in the maintenance of hematopoietic stem cells
2. Incubation of murine bone marrow cells in hypoxia ensures the maintenance of marrow-repopulating ability together with the expansion of committed progenitors
3. Primitive human HPCs are better maintained and expanded in vitro at 1 percent oxygen than at 20 percent
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