Affiliation:
1. Department of Neurology, Knappschaftskrankenhaus, Ruhr-University of Bochum, In der Schornau 23–25, D-44892 Bochum, Germany.
Abstract
SUMMARY Abnormalities of voice and speech performance are common and are early features of Parkinson’s disease (PD) and other hypokinetic rigid syndromes, such as progressive supranuclear palsy. The typical pattern of dysarthria in PD is characterized by reduced loudness and pitch variability, often in combination with abnormalities of voice, articulatory insufficiencies and irregularity of speech rate and rhythm. Recent preliminary investigations on the progression of dysarthria in the course of PD, and on the comparison of dysarthria between PD and progressive supranuclear palsy speakers, justify the assumption that analysis of speech may become a helpful tool for the monitoring of presumably nondopaminergic features and disease progression in PD and for the differential diagnoses of different parkinsonian syndromes.
Reference91 articles.
1. DuffyJR.Motor Speech Disorders: Substrates, Differentials Diagnosis, and Mangement. Elsevier, MO, USA,187–215 (1995).
2. MurdochBE, Whelan BM. Role of the subcortical structures in speech motor control. In:Speech and Language Disorders Associated with Subcortical Pathology. Wiley-Blackwell, NJ, USA,215–243 (2009).
3. Parkinson's disease.
4. Staging of brain pathology related to sporadic Parkinson’s disease
5. Stanley Fahn Lecture 2005: The staging procedure for the inclusion body pathology associated with sporadic Parkinson's disease reconsidered
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