The role of miRNAs in COVID-19 disease-Reference-Cited by-同舟云学术

The role of miRNAs in COVID-19 disease

Published:2021-04 Issue:4 Volume:16 Page:301-306
ISSN:1746-0794
Container-title:Future Virology
language:en
Short-container-title:Future Virology

Author:

Fani Mona¹^ORCID,Zandi Milad²³,Ebrahimi Saeedeh⁴,Soltani Saber²³,Abbasi Samaneh⁵

Affiliation:

1. Department of Pathobiology & Laboratory Sciences, School of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran

2. Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran

3. Research Center for Clinical Virology, Tehran University of Medical Sciences, Tehran, Iran

4. Department of Medical Microbiology, Faculty of Medicine Science, Kerman University of Medical Sciences, Kerman, Iran

5. Abadan Faculty of Medical Science, Abadan, Iran

Abstract

Nowadays, the SARS Coronavirus 2 (SARS-CoV-2) infection is recognized as the primary cause of mortality in humans. SARS-CoV-2 is transmitted through human-to-human contact and is asymptomatic in most patients. In addition to approved vaccines against SARS-CoV-2 infection, miRNAs may also be promising options against this new virus. miRNAs are small and noncoding RNAs 18–25 nucleotides in length that target the mRNAs to degrade them or obstruct their translation miRNAs act as an observer in cells. This study reviewed the literature on the potential role of cellular miRNAs in the SARS-CoV-2-host interplay as a therapeutic option in COVID-19 patients.

Publisher

Future Medicine Ltd

Subject

Virology

Link

https://www.futuremedicine.com/doi/pdf/10.2217/fvl-2020-0389

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