Evidence-based public policy making for medicines across countries: findings and implications for the future

Author:

Godman Brian1234ORCID,Fadare Joseph56ORCID,Kwon Hye-Young7ORCID,Dias Carolina Zampirolli8ORCID,Kurdi Amanj139ORCID,Dias Godói Isabella Piassi1011ORCID,Kibuule Dan12ORCID,Hoxha Iris13,Opanga Sylvia14,Saleem Zikria15ORCID,Bochenek Tomasz16ORCID,Marković-Peković Vanda17ORCID,Mardare Ileana18ORCID,Kalungia Aubrey C19ORCID,Campbell Stephen2021ORCID,Allocati Eleonora22,Pisana Alice23,Martin Antony P24ORCID,Meyer Johanna C3ORCID

Affiliation:

1. Strathclyde Institute of Pharmacy & Biomedical Sciences, University of Strathclyde, Glasgow G4 0RE, UK

2. Division of Clinical Pharmacology, Karolinska Institute, Karolinska University Hospital Huddinge, SE-141 86, Stockholm, Sweden

3. School of Pharmacy, Sefako Makgatho Health Sciences University, Pretoria, South Africa

4. School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia

5. Department of Pharmacology & Therapeutics, Ekiti State University, Ado-Ekiti, Nigeria

6. Department of Medicine, Ekiti State University Teaching Hospital, Ado-Ekiti, Nigeria

7. Division of Biology and Public Health, Mokwon University, Daejeon, Korea

8. Graduate Program in Public Health, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

9. Department of Pharmacology, College of Pharmacy, Hawler Medical University, Erbil, Iraq

10. Institute of Health & Biological Studies – Universidade Federal do Sul e Sudeste do Pará, Avenida dos Ipês, s/n, Cidade Universitária, Cidade Jardim, Marabá, Pará, Brazil

11. Researcher of the Group (CNPq) for Epidemiological, Economic and Pharmacological Studies of Arboviruses (EEPIFARBO) – Universidade Federal do Sul e Sudeste do Pará; Avenida dos Ipês, s/n, Cidade Universitária, Cidade Jardim, Marabá, Pará, Brazil

12. Department of Pharmacy Practice & Policy, Faculty of Health Sciences, University of Namibia, Windhoek, Namibia

13. Department of Pharmacy, Faculty of Medicine, University of Medicine Tirana, Albania

14. Department of Pharmaceutics & Pharmacy Practice, School of Pharmacy, University of Nairobi, Nairobi, Kenya

15. Faculty of Pharmacy, University of Lahore, Lahore, Pakistan

16. Department of Nutrition & Drug Research, Faculty of Health Sciences, Jagiellonian University Medical College, Krakow, Poland

17. Department of Social Pharmacy, University of Banja Luka, Faculty of Medicine, Banja Luka, Republic of Srpska, Bosnia & Herzegovina

18. “Carol Davila” University of Medicine & Pharmacy, Bucharest, Romania

19. Department of Pharmacy, University of Zambia, Lusaka, Zambia

20. Centre for Primary Care, Division of Population Health, Health Services Research & Primary Care, University of Manchester, Manchester, M13 9PL, UK

21. NIHR Greater Manchester Patient Safety Translational Research Centre, School of Health Sciences, University of Manchester, Manchester, UK

22. Istituto di Ricerche Farmacologiche ‘Mario Negri’ IRCCS, Milan, Italy

23. Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden

24. Faculty of Health & Life Sciences, The University of Liverpool, Brownlow Hill, Liverpool, L69 3BX, UK

Abstract

Aim: Global expenditure on medicines is rising up to 6% per year driven by increasing prevalence of non-communicable diseases (NCDs) and new premium priced medicines for cancer, orphan diseases and other complex areas. This is difficult to sustain without reforms. Methods: Extensive narrative review of published papers and contextualizing the findings to provide future guidance. Results: New models are being introduced to improve the managed entry of new medicines including managed entry agreements, fair pricing approaches and monitoring prescribing against agreed guidance. Multiple measures have also successfully been introduced to improve the prescribing of established medicines. This includes encouraging greater prescribing of generics and biosimilars versus originators and patented medicines in a class to conserve resources without compromising care. In addition, reducing inappropriate antibiotic utilization. Typically, multiple measures are the most effective. Conclusion: Multiple measures will be needed to attain and retain universal healthcare.

Publisher

Future Medicine Ltd

Subject

Health Policy

Reference353 articles.

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