Other tyrosine kinase inhibitors in development and future directions

Author:

Knippschild Uwe1,Peifer Christian2,Bischof Joachim3,Kramer Klaus4

Affiliation:

1. Uwe Knippschild is professor in the Department of General-, Visceral-, and Transplantation Surgery of the University of Ulm (Germany). His PhD was in tumor virology, working on the role of phosphorylation in regulating the activity of oncogenes and tumor-suppressor proteins. He then worked as a postdoc at the Heinrich–Pette–Institute for Experimental Virology in Hamburg and at the Biomedical Research Center in Dundee, Scotland. His research interests are now focused on malignant diseases especially on...

2. Christian Peifer earned his PhD in Medicinal Chemistry from the University of Mainz and was postdoc at University of Tübingen (Germany) and the MRC in Dundee, Scotland. He worked as project manager for the company Schrödinger (Molecular Modeling Software) and was appointed as professor at the University of Kiel (Germany) in 2010. His research interest is focusing on a medicinal chemistry platform consisting of design, organic synthesis, and biological evaluation to develop cell permeable small molecule...

3. Joachim Bischof graduated in Molecular Medicine at the University of Ulm (Germany) and acquired profound experience in the field of signal transduction research within the last 5 years. As research associate in basic medical research he is focused on providing insight to the molecular basics of malignant proliferative diseases. His work successfully contributed to the discovery and development of new kinase inhibitor compounds as well as to a deeper understanding of certain cellular signaling networks.

4. Klaus Kramer is an assistant professor in the Department of General-, Visceral-, and Transplantation Surgery of the University of Ulm (Germany). His clinical expertise encompasses the management of malignant diseases of the gastrointestinal tract. His research focuses on signaling pathways that drive carcinogenesis of gastrointestinal stroma tumors (GISTs), the identification of new prognostic markers and on molecular targeted therapies for GISTs. Furthermore, he has established a GIST registry including...

Publisher

Future Medicine Ltd

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