An interdisciplinary approach to personalized medicine: case studies from a cardiogenetics clinic

Author:

Erskine Kathleen E1,Griffith Eleanor2,DeGroat Nicole3,Stolerman Marina4,Silverstein Louise B5,Hidayatallah Nadia5,Wasserman David6,Paljevic Esma7,Cohen Lilian8,Walsh Christine A9,McDonald Thomas10,Marion Robert W11,Dolan Siobhan M12

Affiliation:

1. Department of Obstetrics & Gynecology & Women’s Health, Division of Reproductive Genetics, Albert Einstein College of Medicine/Montefiore Medical Center, 1695 Eastchester Road, Suite 301, Bronx, NY, USA

2. University OBGYN Associates, Ambulatory Care Center, C1673, UMDNJ, 140 Bergen Street, Newark, NJ 07103, USA

3. Department of Obstetrics & Gynecology & Women’s Health, Division of Reproductive Genetics, Albert Einstein College of Medicine/Montefiore Medical Center, 1300 Morris Park Avenue, Mazer 632, Bronx, NY, USA

4. Private Practice, 425 E 86th Street, Suite 1A, New York, NY, USA

5. Ferkauf Graduate School of Psychology, Yeshiva University, 1300 Morris Park Avenue, Bronx, NY, USA

6. Center for Ethics at Yeshiva University, 500 W 185th Street, New York, NY, USA

7. Pediatric Heart Center, Children’s Hospital at Montefiore, 3415 Bainbridge Avenue, Bronx, NY, USA

8. Division of Medical Genetics, Weill Cornell Medical College/New York Presbyterian Hospital, 505 East 70th Street, Helmsley Tower, 3rd Floor, New York, NY, USA

9. Pediatric Dysrhythmia Center, Children’s Hospital at Montefiore, 3415 Bainbridge Avenue, Bronx, NY, USA

10. Departments of Medicine/Cardiology & Molecular Pharmacology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Forchheimer G35, Bronx, NY, USA

11. Divisions of Developmental Medicine & Genetics, Children’s Hospital at Montefiore, 3415 Bainbridge Avenue, Bronx, NY, USA

12. Department of Obstetrics & Gynecology & Women’s Health, Division of Reproductive Genetics, Albert Einstein College of Medicine/Montefiore Medical Center, 1300 Morris Park Avenue, Mazer 634, Bronx, NY 10461 USA.

Abstract

In the genomic age, the challenges presented by various inherited conditions present a compelling argument for an interdisciplinary model of care. Cardiac arrhythmias with a genetic basis, such as long QT syndrome, require clinicians with expertise in many specialties to address the complex genetic, psychological, ethical and medical issues involved in treatment. The Montefiore–Einstein Center for CardioGenetics has been established to provide personalized, interdisciplinary care for families with a history of sudden cardiac death or an acute cardiac event. Four vignettes of patient care are presented to illustrate the unique capacity of an interdisciplinary model to address genetic, psychological, ethical and medical issues. Because interdisciplinary clinics facilitate collaboration among multiple specialties, they allow for individualized, comprehensive care to be delivered to families who experience complex inherited medical conditions. As the genetic basis of many complex conditions is discovered, the advantages of an interdisciplinary approach for delivering personalized medicine will become more evident.

Publisher

Future Medicine Ltd

Subject

Pharmacology,Molecular Medicine,General Medicine

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