1. Department of Medicine, University of Cape Town, Cape Town, South Africa
2. Vaccines for Africa Initiative, Institute of Infectious Disease & Molecular Medicine, University of Cape Town, Cape Town, South Africa
3. Department of Medicine, New Somerset Hospital, Cnr Beach & Lower Portswood Road, Green Point, Cape Town 8001, Western Cape, South Africa
4. Division of Epidemiology & Biostatistics, School of Public Health & Family Medicine, University of Cape Town, Cape Town, South Africa
5. Clinical Infectious Diseases Research Initiative, Institute of Infectious Disease & Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory, Cape Town 7925, South Africa
6. Department of Medicine, Imperial College London, W2 1PG, UK
7. Medical Research Council, National Institute of Medical Research, London, NW7 1AA, UK