Ethical considerations in the implementation of nutrigenetics/nutrigenomics

Author:

Hurlimann Thierry1,Robitaille Julie2,Vohl Marie-Claude2,Godard Béatrice1

Affiliation:

1. Public Health Research Institute – University of Montreal (IRSPUM), PO Box 6128, Station Centre-ville, Montreal, QC, H3C 3J7, Canada

2. Institute of Nutrition & Functional Foods (INAF) & School of Nutrition, Université Laval, 2440 Hochelaga Blvd, Room 2729-N, Quebec City, QC, Canada

Abstract

Awareness of ethical issues that may be raised by the implementation of nutrigenetic/nutrigenomic (NGx) testing and personalized nutrition, at an individual or a public health level, is crucial to ensure the latter's sound and effective implementation. NGx tests that are currently offered or developed have different natures and scopes. We provide an example of NGx testing on the MTHFR gene to illustrate the current challenges when it comes to grasp the meaning of the results of such testing. In addition, NGx testing is developed within an evolving landscape of new genomic technologies and occurs at a time when public health policies mainly focus on preventive and predictive healthcare, with an emphasis on increased individual responsibility. The ethical issues raised by such a context and the genetic nature of NGx testing both should be carefully evaluated.

Publisher

Future Medicine Ltd

Subject

Pharmacology,Molecular Medicine,General Medicine

Reference81 articles.

1. Clinical utility of genetic and genomic services: a position statement of the American College of Medical Genetics and Genomics

2. Centers for Disease Control and Prevention, Office of Public Health Genomics. ACCE model list of 44 targeted questions aimed at a comprehensive review of genetic testing (2010). www.cdc.gov/genomics/gtesting/acce/acce_proj.htm.

3. Risks of nutrigenomics and nutrigenetics? What the scientists say

4. National Human Genome Research Institute. Frequently asked questions about genetic testing (2015). www.genome.gov/19516567.

5. Reporting Incidental Findings in Genomic Scale Clinical Sequencing—A Clinical Laboratory Perspective

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