Palmoplantar pustular psoriasis induced by adalimumab: a case report and literature review

Author:

Ibis Nurdan1,Hocaoglu Sehriban1,Cebicci Mehtap Aykac1,Sutbeyaz Serap Tomruk1,Calis Havva Talay1

Affiliation:

1. Physical Therapy & Rehabilitation Department, Kayseri Education & Research Hospital, Atatürk Avenue, No:78, 38010 Kayseri, Turkey

Abstract

TNF-α inhibitors (anti-TNF-α) are agents increasingly used in the treatment of rheumatic diseases resistant to classical disease-modifying treatment and they provide significant improvement of disease activity. However, these agents have many cutaneous side effects including psoriasis. Numerous reports of the induction or worsening of psoriasis in patients treated with TNF antagonists indicate that this is not a rare phenomenon. In this study, we present a patient with ankylosing spondylitis who developed palmoplantar pustular psoriasis after receiving anti-TNF-α therapy for 4 months.

Publisher

Future Medicine Ltd

Subject

Oncology,Immunology,Immunology and Allergy

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