Bevacizumab in recurrent glioblastoma: open issues

Author:

Franceschi Enrico1,Bartolotti Marco1,Brandes Alba A1

Affiliation:

1. Department of Medical Oncology, Azienda USL, Bellaria Hospital – IRCCS Institute of Neurological Sciences, Bologna, Italy

Abstract

Recurrent glioblastoma represents a challenge in neuro-oncology since the prognosis is poor and current therapeutic options are limited. Bevacizumab has demonstrated activity in this setting in various clinical trials and has been approved by US FDA for the treatment of recurrent glioblastoma. Nevertheless, many issues still exist. In this article, we summarized the principal subjects of controversies that surround bevacizumab and its use in the treatment of recurrent glioblastoma.

Publisher

Future Medicine Ltd

Subject

Cancer Research,Oncology,General Medicine

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