Dyslipidemia, atherosclerosis and cardiovascular disease: an increasingly important triad in an aging population living with HIV

Author:

O’Halloran Jane A1,Satchell Claudette S2,Mallon Patrick WG34

Affiliation:

1. HIV Molecular Research Group, University College Dublin School of Medicine and Medical Science, Catherine McAuley Education & Research Centre, Nelson Street, Dublin 7, Ireland.

2. Justice Health Research Program, Kirby Institute, University of New South Wales, Sydney, NSW, Australia

3. HIV Molecular Research Group, University College Dublin School of Medicine and Medical Science, Catherine McAuley Education & Research Centre, Nelson Street, Dublin 7, Ireland

4. Department of Infectious Diseases, Mater Misericordiae University Hospital, Dublin, Ireland

Abstract

As a result of major advances in the management of HIV over the last two decades, patients living with HIV are now encountering comorbidities commonly associated with aging. Cardiovascular disease is the leading cause of death worldwide. As the population living with HIV ages, understanding cardiovascular disease in the setting of HIV is of increasing importance. This review examines the complex interplay between cardiovascular disease, HIV infection and the drugs used to treat it, with particular emphasis on the contribution of dyslipidemia.

Publisher

Future Medicine Ltd

Subject

Virology

Reference116 articles.

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3. RodgerA, Lodwick R, Schechter Met al.Mortality in patients with well-controlled HIV and high CD4 counts in the cART arms of the SMART and ESPRIT randomized clinical trials compared to the general population. Presented at:19th Conference on Retroviruses and Opportunistic Infections (CROI 2012). WA, USA, 5–8 March 2012 (Abstract 638).

4. CDC. HIV/AIDS Surveillance Report, 2005. US Department of Health and Human Services, Centres for Disease Control and Prevention, GA, USA,17,1–54 (2007).

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