Pimecrolimus cream 1% in the treatment of pediatric atopic dermatitis

Author:

Lynde Charles1

Affiliation:

1. University of Toronto, 5762 Highway 7 East, Suite 201 Markham, Ontario, L3P 1A8, Canada.

Abstract

Atopic dermatitis (AD) is a common condition affecting an estimated 10–15% of school-aged children. It has a cyclical disease course involving periods of clear skin, early signs/symptoms and flares. Traditionally, pediatric AD was treated mainly with topical corticosteroids; however, nonsteroidal topical calcineurin inhibitors, pimecrolimus 1% cream and tacrolimus 0.03% ointment are welcome additions to the therapeutic arsenal. Pimecrolimus is indicated for mild and moderate AD and tacrolimus for moderate and severe disease. As topical calcineurin inhibitors are increasingly accepted in the AD ‘continuum of care’, a need to distinguish the optimal roles of these agents has emerged. This article reviews clinical and safety data of pimecrolimus 1% cream in pediatric AD compared with vehicle and tacrolimus 0.03% ointment.

Publisher

Future Medicine Ltd

Subject

Pediatrics,Pediatrics, Perinatology, and Child Health

Reference53 articles.

1. McCallCO, Lawley TJ: Eczema, psoriasis, cutaneous infections, acne and other common skin disorders. In:Harrison’s Principles of Internal Medicine (16th Edition). Kasper DL, Isselbacher KJ (Eds). McGraw-Hill Medical Publishing Division, Toronto, Canada,288–296 (2005).

2. RajkaG: Clinical aspects. In:Essential Aspects of Atopic Dermatitis. Rajka G (Ed.). Springer-Verlag Berlin, Germany4–55 (1989).

3. Atopic dermatitis: Predictions, expectations, and outcomes

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3