Molecular diagnosis of bacteremia in a pediatric intensive care unit: a step forward-Reference-Cited by-同舟云学术

Molecular diagnosis of bacteremia in a pediatric intensive care unit: a step forward

Published:2022-05 Issue:7 Volume:17 Page:505-510
ISSN:1746-0913
Container-title:Future Microbiology
language:en
Short-container-title:Future Microbiology

Author:

Falces-Romero Iker¹²^ORCID,Román-Hernández Carmen³,Schuffelmann-Gutiérrez Cristina³,Laplaza-González María³,Escosa-García Luis⁴,Bloise Iván¹,Romero-Gómez María P¹,Verdú-Sánchez Cristina³,Calderón-Llopis Belén³,Amores-Hernández Irene³,Gómez-Zamora Ana³,Río-García Miguel³,Menéndez-Suso Juan J³,Rodríguez-Álvarez Diego³,Pérez-Acosta Elena³,Rodríguez-Rubio Miguel³,Álvarez-Rojas Elena³,la Oliva Pedro de³,Mingorance Jesús¹,Martínez-Romillo Paloma D³,García-Rodríguez Julio¹,Cendejas-Bueno Emilio¹^ORCID

Affiliation:

1. Clinical Microbiology & Parasitology Department, Hospital Universitario La Paz, IdiPaz, Madrid, Spain

2. CIBERINFEC, Instituto de Salud Carlos III, Madrid, Spain

3. Pediatric Intensive Care Department, Hospital Universitario La Paz, Madrid, Spain

4. Department of Infectious Diseases & Tropical Pediatrics, Hospital Universitario La Paz, Madrid, Spain

Abstract

Aim: T2Bacteria® Panel detects six ESKAPE pathogens in around 3.5 h directly in whole blood. Our aim was to compare T2Bacteria with simultaneous blood culture in critically ill children with suspected bloodstream infection. Materials & methods: Retrospective study of critically ill children admitted to our tertiary-care center (2018–2020). Results: A total of 60 patients were recruited, including 63 episodes and 75 T2Bacteria/blood cultures were performed. Overall agreement between T2Bacteria and blood culture was 78.7% with a discordance of 21.3% (16/75 samples). Conclusion: T2Bacteria Panel may be useful in critically ill children providing an accurate and fast diagnosis of bacteremia directly from blood sample and detecting pathogens not recovered in blood cultures.

Publisher

Future Medicine Ltd

Subject

Microbiology (medical),Microbiology

Link

https://www.futuremedicine.com/doi/pdf/10.2217/fmb-2021-0154

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