Immune reconstitution inflammatory syndrome in HIV-positive patients: a relatively new and not fully understood phenomenon

Author:

Arendt Gabriele1,Nolting Thorsten2

Affiliation:

1. Department of Neurology, University of Duesseldorf, Medical Faculty, Moorenstr. 5, 40225 Duesseldorf, Germany.

2. Department of Psychiatry, University Hospital of Duesseldorf/Rheinische Kliniken (LVR), Germany

Abstract

The article describes the immune reconstitution inflammatory syndrome in HIV-positive patients as a phenomenon detected in recent years as a consequence of HAART initiation in patients with a severely compromised immune system and rapid improvement under HAART. Pathophysiology, clinical presentation and therapeutic options are discussed.

Publisher

Future Medicine Ltd

Subject

Pharmacology (medical),Infectious Diseases,Virology,Dermatology,Drug Discovery,Pharmacology

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