Epigenetic dysregulation in follicular lymphoma-Reference-Cited by-同舟云学术

Epigenetic dysregulation in follicular lymphoma

Published:2016-01 Issue:1 Volume:8 Page:77-84
ISSN:1750-1911
Container-title:Epigenomics
language:en
Short-container-title:Epigenomics

Author:

Araf Shamzah¹,Okosun Jessica¹,Koniali Lola¹,Fitzgibbon Jude¹,Heward James¹

Affiliation:

1. Centre for Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, John Vane Science Centre, Charterhouse Square, London, EC1M 6BQ, UK

Abstract

The adoption of next-generation sequencing technologies has led to a remarkable shift in our understanding of the genetic landscape of follicular lymphoma. While the disease has been synonymous with the t(14;18), the prevalence of alterations in genes that regulate the epigenome has been established as a pivotal hallmark of these lymphomas. Giant strides are being made in unraveling the biological consequences of these alterations in tumorigenesis opening up new opportunities for directed therapies.

Publisher

Future Medicine Ltd

Subject

Cancer Research,Genetics

Link

https://www.futuremedicine.com/doi/pdf/10.2217/epi.15.96

Reference66 articles.

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