A pharmacist’s role in the individualization of treatment of HIV patients

Author:

Hernández Arroyo María Jesús1,Cabrera Figueroa Salvador Enrique23,Valverde Merino María Paz3,Hurlé Alfonso Domínguez-Gil4

Affiliation:

1. Pharmacy Service, Primary Care Management of Zamora, Zamora, Spain

2. Pharmacy Institute, University Austral of Chile, Valdivia, Chile

3. Pharmacy Service, University Hospital of Salamanca, Paseo de San Vicente 58, 37007 Salamanca, Spain

4. Department of Pharmacy & Pharmaceutical Technology, University of Salamanca, Salamanca, Spain

Abstract

The pharmacological treatment of HIV is complex and varies considerably among patients, as does the response of patients to therapy, requiring treatment plans that are closely tailored to individual needs. Pharmacists can take an active role in individualizing care by employing their knowledge of pharmacokinetics and pharmacogenetics and by interacting directly with patients in counseling sessions. These strategies promote the following: maintenance of plasma concentrations of antiretroviral agents within therapeutic ranges, prediction of pharmacological response of patients with certain genetic characteristics, and clinical control of HIV through the correct use of antiretroviral treatments. Together, these strategies can be used to tailor antiretroviral therapy to individual patients, thus improving treatment efficacy and safety.

Publisher

Future Medicine Ltd

Subject

Pharmacology,Molecular Medicine,General Medicine

Reference172 articles.

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2. Inhibiting HIV-1 Entry with Fusion Inhibitors

3. Department of Human Health Service (DHHS) Panel on Antiretroviral Guidelines for Adults and Adolescents. Guideline for the use of antiretroviral agents in HIV-1-infected adults and adolescents (2015). http://aidsinfo.nih.gov/contentfiles/lvguidelines/adultandadolescentgl.pdf.

4. Panel de expertos de Gesida y Plan Nacional sobre el Sida. Documento de consenso de Gesida/Plan Nacional sobre el Sida respecto al tratamiento antirretroviral en adultos infectados por el virus de la inmunodeficiencia humana (2015). www.gesida-seimc.org/contenidos/guiasclinicas/2015/gesida-guiasclinicas-2015-tar.pdf.

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