The Learning-Adapting-Leveling model: from theory to hypothesis of steps for implementation of basic genome-based evidence in personalized medicine

Author:

Lal Jonathan A1,Vaidya Anil2,Gutiérrez-Ibarluzea Iñaki3,Dauben Hans-Peter4,Brand Angela5

Affiliation:

1. Institute for Public Health Genomics, Department of Genetics & Cell Biology, School for Oncology & Developmental Biology (GROW), Faculty of Health Medicine & Life Sciences, Maastricht University, Universiteitssingel 50, 6229 ER Maastricht, The Netherlands.

2. Department of Clinical Epidemiology & Medical Technology Assessment (KEMTA), School for Public Health & Primary Care (CAPHRI), Faculty of Health, Medicine & Life Sciences, Maastricht University Medical Center, 6202 AZ Maastricht, The Netherlands

3. Osteba, Basque Office for Health Technology Assessment, Department of Health, Basque Government, Donostia-San Sebastian, 1 01010-Vitoria-Gasteiz, Basque Country, Spain

4. German Institute for Medical Documentation & Information – DIMDI, Waisenhausgasse 36–38a, 50676 Cologne, Germany

5. Institute for Public Health Genomics, Department of Genetics & Cell Biology, School for Oncology & Developmental Biology (GROW), Faculty of Health Medicine & Life Sciences, Maastricht University, Universiteitssingel 50, 6229 ER Maastricht, The Netherlands

Abstract

We see a backlog in the effective and efficient integration of personalized medicine applications such as genome-based information and technologies into healthcare systems. This article aims to expand on the steps of a published innovative model, which addresses the bottleneck of real-time integration into healthcare. We present a deconstruction of the Learning-Adapting-Leveling model to simplify the steps. We found out that throughout the technology transfer pipeline, contacts, assessments and adaptations/feedback loops are made with health needs assessment, health technology assessment and health impact assessment professionals in the same order by the academic–industrial complex, resulting in early-on involvement of all stakeholders. We conclude that the model steps can be used to resolve the bottleneck of implementation of personalized medicine application into healthcare systems.

Publisher

Future Medicine Ltd

Subject

Pharmacology,Molecular Medicine,General Medicine

Cited by 5 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3