The importance of including African populations in pharmacogenetics studies of warfarin response-Reference-Cited by-同舟云学术

The importance of including African populations in pharmacogenetics studies of warfarin response

Published:2022-01 Issue:1 Volume:23 Page:1-4
ISSN:1462-2416
Container-title:Pharmacogenomics
language:en
Short-container-title:Pharmacogenomics

Author:

Dandara Collet¹^ORCID,Ndadza Arinao¹,Soko Nyarai¹

Affiliation:

1. Department of Pathology & Institute of Infectious Diseases & Molecular Medicine, Pharmacogenomics & Drug Metabolism Research Group, Division of Human Genetics, Faculty of Health Sciences, University of Cape Town, Observatory 7925, South Africa

Abstract

Tweetable abstract Warfarin will remain in use for a long time to come, thus inclusion of African populations in pharmacogenomics is essential to be able to identify all possible biomarkers that are potential predictors for warfarin drug response.

Funder

National Research Foundation

Medical Research Council, South Africa

Publisher

Future Medicine Ltd

Subject

Pharmacology,Genetics,Molecular Medicine

Link

https://www.futuremedicine.com/doi/pdf/10.2217/pgs-2021-0142

Reference19 articles.

1. Anticoagulation in sub‐Saharan Africa: Are direct oral anticoagulants the answer? A review of lessons learnt from warfarin

2. Direct oral anticoagulants versus warfarin: is new always better than the old?

3. Improving anticoagulation in sub‐Saharan Africa: What are the challenges and how can we overcome them?

4. Profiling of warfarin pharmacokinetics‐associated genetic variants: Black Africans portray unique genetic markers important for an African specific warfarin pharmacogenetics‐dosing algorithm

5. Influence of CYP2C9, VKORC1, and CYP4F2 polymorphisms on the pharmacodynamic parameters of warfarin: a cross-sectional study

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3. Warfarin pharmacogenomics in African populations: the importance of ethnicity-based algorithms;Pharmacogenomics;2022-09