1. Department of Biology, Laboratory of Genetics, University of Patras, Patras, Greece
2. Department of Hygiene & Epidemiology, Medical School, University of Ioannina, Ioannina, Greece
3. Institute of Biosciences, University Research Center of loannina, Ioannina, Greece
4. Department of Epidemiology & Biostatistics, MRC Centre for Environment and Health, School of Public Health, Faculty of Medicine, Imperial College London, St Mary's Campus, Norfolk Place, London, W2 1PG, UK